Researchers in Iran have found a Middle Eastern yogurt drink which is known as “doogh” and fortified with vitamin D decreases inflammatory markers in people with type2 diabetes. Chris Kaiser has reported for MedPage Today “Yogurt Drink Good for Diabetes.” Tirang Neyestani, PhD, of Beheshti University of Medical Sciences in Tehran, Iran, and colleagues have reported participants in their study who drank the doogh fortified with vitamin D, or vitamin D plus calcium, had decreased levels of highly sensitive C-reactive protein and several interleukin proteins, among other markers of inflammation.
The researchers also reported online in the Journal of Clinical Endocrinology and Metabolism that those drinking the fortified concoctions of doogh had significantly higher levels of adiponectin. Adiponectin is a hormone which is known to have anti-inflammatory properties and to regulate the metabolism of glucose. It has been found in previous research that higher levels of adiponectin were associated with a lower risk of type 2 diabetes. In this study, the researchers conducted a double-blind, randomized, controlled trial over 12 weeks in 90 patients who were diagnosed with type 2 diabetes.
The participants were randomized equally either to plain doogh, doogh fortified with vitamin D, or doogh fortified with vitamin D and calcium. The participants drank two bottles of the liquid yogurt per day. The researchers said both groups with fortified drinks showed significant improvement of vitamin D status at the end of 12 weeks, “confirming high bioavailability of vitamin D in doogh.” It was also found that the inflammatory markers that significantly decreased at the end of 12 weeks were C-reactive protein, interleukin(IL)-1 beta, IL-6, fibrinogen and retinol binding protein (RBP)-4.
The researchers have stated “This is the first study to show that vitamin D with or without extracalcium resulted in a significant decrease in these particular inflammatory biomarkers, as well as an increase in adiponectin and RBP-4.” They has also said “Our study showed for the first time that adiponectin, a substance secreted by fat tissue that has an anti-inflammatory effect, increased when calcium and vitamin D-fortified doogh was consumed.” This research could have interesting implications for the prevention and treatment of type 2 diabetes in the United States.
Mandel News Service